OcuPhase Eyedrops

(351 customer reviews)

  • Contains 1% NAC (N-acetylcarnosine), a naturally occurring antioxidant and antiglycating agent.
  • Safe for use by people with: Cataracts, Glaucoma, Age-Related Macular Degeneration (ARMD/AMD), and Floaters.
  • Research with N-acetylcarnosine, as with it’s parent compound carnosine, demonstrates that it is effective not only in supporting healthy vision but also in increasing the transmissivity of the lens to light.
  • Helps to combat “dry eye” and other forms of eye irritation, such as blurry vision, night glare, and computer eye strain.
  • Each box of OcuPhase contains two resealable vials containing a total of about 200 drops.


Qty Discount Unit Price
3 - 5 Mix and Match Discount $37.95
6 - 11 Mix and Match Discount $35.96
12 + Mix and Match Discount $33.96


Suggested Use: For general preventive use, the recommended amount is 1–2 drops daily. Those with eye problems may want to use 2 drops twice daily or as needed.

OcuPhase also contains 1% N-acetylcarnosine, a naturally occurring antioxidant and antiglycating agent that helps protect the active ingredients from glycation. OcuPhase also contains ophthalmic lubricating agents to combat “dry eye” and other forms of eye irritation. Each box contains two vials containing five milliliters each.

Each package contains two resealable vials containing a total of about 200 drops, which allows for only a small amount of product to be exposed to oxygen at a time. Unopened vials can be stored in the refrigerator to extend shelf life.


  • If you experience eye pain, changes in vision, continued redness or irritation of the eye, or if the condition worsens or persists for more then 72 hours, discontinue use and consult a doctor.
  • To avoid contamination, do not touch tip of container to any surface.
  • Replace cap after using.
  • Do not use if seal is broken.
  • If solution changes color or becomes cloudy, do not use.

Not recommended for pregnant or nursing women.


Active Ingredients: Glycerin (lubricant) 1.0%, hydroxypropylmethylcellulose (lubricant) 0.15%

Inactive Ingredients: Sterile water (ophthalmic grade isotonic solution, pH 6.3 to 6.4), N-acetylcarnosine (NAC) 1.0%, buffered with boric acid, citric acid, and potassium bicarbonate, and, as a preservative, purified benzyl alcohol.


Good nutrition is a key element of preventing numerous age-related issues, including the health of our eyes. As we age our eyes become more susceptible to a host of challenges that can lead to irritation, discomfort and changes to vision. Colors may be dulled or distorted, and there may be an annoying halo of light around bright objects, causing a glare effect.

Applying lubricating eye drops several times a day can help to alleviate discomfort. Additionally, a number of nutrients have been shown to benefit eye health and good vision. One of these, carnosine, is a dipeptide consisting of two amino acids (alanine and histidine) connected by a chemical bond. Based on research performed mainly by Russian scientists, it is believed that carnosine’s antioxidant properties support healthy vision by inhibiting a chemical process called glycation.

Glycation leads to deleterious chemical complexes called AGEs (advanced glycation end products) that result from common but undesirable reactions between blood sugars, such as glucose, and proteins in many parts of our bodies, including the lenses of our eyes. The sugar-protein complexes become chemically cross-linked and degrade cellular functions. The aptly named AGEs are thought to be an important factor in the aging process.

Carnosine eye drops have been shown to aid in delaying vision senescence in humans by restoring the natural structure of proteins in the lens.


N-acetylcarnosine (NAC), like its parent compound, carnosine, occurs naturally throughout the human body. Both compounds are found primarily in the heart and skeletal muscles (the word carnosine is derived from the Latin word for flesh) and in the brain. Carnosine was discovered in 1900 in Russia, and it is in Russia that most of the recent research on the N-acetylcarnosine derivative has been carried out. Research with N-acetylcarnosine, as with carnosine, demonstrates that it is effective for improving transmissivity of light through the lens.

The structural difference between NAC and carnosine is that one hydrogen atom in carnosine replaces an acetyl group (CH3CO-), and this substitution occurs at a nitrogen atom. An important chemical difference between carnosine and N-acetylcarnosine is that carnosine is relatively insoluble in lipids (fats and fatty compounds), whereas N-acetylcarnosine is relatively soluble in lipids (as well as in water).

This means that N-acetylcarnosine may pass through the lipid membranes of the corneal and lens cells more easily than carnosine, and may thereby gain access more readily to the cells interior, which is primarily aqueous. There, the N-acetylcarnosine is gradually broken down to carnosine (and, perhaps, to histidine), which then exerts its beneficial effects.


Carnosine and N-acetylcarnosine eye drops appear to be a safe, effective means for supporting eye health, comfort and quality of vision in aging humans.

* These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.


What is the recommended daily use of OcuPhase?

For general preventive use, the recommended amount is 1–2 drops daily. Those with eye problems may want to use 2 drops twice daily or as needed.

Can children use OcuPhase?

OcuPhase eyedrops are not recommended for children under the age of 12 years.

What if I experience any discomfort when using OcuPhase eyedrops?

If the eye tissue becomes more inflamed, red, irritated or uncomfortable after using this product, immediately discontinue the use of product and consult an eye physician if necessary.

351 reviews for OcuPhase Eyedrops

Based on 351 reviews
Showing 25 of 351 reviews (3 star). See all 351 reviews
  1. Barbara Krieger (verified owner)

    Very soothing but my eyes get a little blurry

    Barbara Krieger

  2. Vinaya Baron

    Been using for 2 weeks and am noticing some changes.

    Vinaya Baron

  3. Elton Johnson

    My wife is a candidate for cataract surgery. Before going to that extreme we decided to give OcuPhase a try based on the reviews. It’s been two weeks and she reports light is brighter and objects are not as blurry as before. She has reported some stinging when I administer the drops (twice a day) We’ve decided to go at least six months to ensure a measurable, beneficial change is actually taking place. I am cautiously optimistic.

    Elton Johnson

  4. Alfred Farrugia (verified owner)

    I have not visited the eye doctor yet, but I am confident that he will note that if there has not been an improvement, my eyes have not deteriorated.

    Alfred Farrugia

  5. lea reedy

    so far, okay. have only used for 3 months so I don’t expect anything yet. will give it another 3 to 6 months and see if anything has changed.

    lea reedy

  6. Claude Poe

    I have been using the drops for only a week now. It looks like my left eye is getting better, but it is still to early to tell. I hope to follow up with a update in about a month.

    Claude Poe

  7. teresa robinson

    helps with dry eyes and made driving with cataracts clearer and easier.woulsd recommend for those with mild cataracts as it seems to help rather than the radical surgery as the other option.

    teresa robinson

  8. Sheryl Hiatt

    I have been using OcuPhase Eye drops for about 3 months now. I will continue to use them for at least another 3 months in the hopes of improving my eyesight and to hopefully eliminate the need to have cataract surgery. At the end of the 6 months I will plan on having an eye exam and will compare it to my last eye exam and see if there has been an improvement to my eyesight.

    Sheryl Hiatt

  9. Benny Ellis

    After t6hree weeks of use my wife says that there seems to be slight improvement. She will continue to use and observe any future change in her vision

    Benny Ellis

  10. Linda Schrack

    Just started my second bottle so I can’t really say I notice much yet, except that my eyes do not feel strained like they did. Can update when I have been using them longer.

    Linda Schrack

  11. Frank Willy

    I was told by my ophthalmologist that I have cataracts so I decided to use the OcuPhase eye drops.I have been using them for over 6 months when I went back to him and he says I have them as bad as I before. I do notice that the cloudyness has cleared up but my eye sight still remains poor. I would like to go to another optometrist and have another eye exam for some new glasses. It has been close to a year that I have been using the drops and feel an improvement and will have another eye exam

    Frank Willy

  12. Aubrey Langhorne (verified owner)

    Seems to be working very well.
    I have increased my reading of smaller letters.

    Aubrey Langhorne

  13. Peter Sak

    There seems to be some improvement but I’ll know for sure
    next month when I have my optometry appointment.

    Peter Sak

  14. milton gorham

    seems to lube eyes and they may be more relaxed thru the next few hours.. way too early to tell about cataracts

    milton gorham

  15. William Stachura

    I have cataracts, primarily though, my main concern is my right eye which is quite cloudy at the periphery. My opthmaologist wants to schedule me for surgery. I have read some promising studies done on n-acetylcarnosine and so I have opted to try these for six months and see if there is any benefit. I have been using these now for almost a month ( 2 drops in the right eye, 3 times a day). It is much too soon to say if or how much these drops will ultimately help, I have already noticed a substantial improvement in my acuity, and the lack of artifacts and halos under bright lights. I have not noticed any side effects and my eyesight has certainly not worsened. So I will continue to use them and see if things continue to improve.

    William Stachura

  16. Amelia Ranieri

    I have been using Ocuphase eyedrops for only two weeks. There appears to be an improvement in my vision so I am inclined to keep using it. I am also hoping it will eliminate or dissolve minor issues in both of my eyes.

    Amelia Ranieri

  17. Ronald Green

    The Eye Drops seem to helping my vision somewhat. When I first started using them the improvement was dramatic. When I was sick recently the results seemed to decrease somewhat. I believe the eye drops are helping me somewhat, but I am a long way from a complete resolution.

    Ronald Green

  18. Kristine Michael

    I have a slow growing condition in one eye which is why I purchased OcuPhase. I have been using the drops for a few months now, but am not certain how effective it has been, as I have not had a follow up visit to my eye doctor.

    Kristine Michael

  19. frank willy

    One my 5th tube of OcuPhase waiting for results

    frank willy

  20. Mary Griffith

    I have been using them for a month and cancelled my eye surgery to see if they really will dissolve my issues. Will let you know when that happens.

    Mary Griffith

  21. Wilflect Bill Bass

    I’m using the OcuPhase eye drops, but I’m unable to assess at this moment, I ‘m continuign to use the eye drops daily..too early to tell the results

    Wilflect Bill Bass

  22. Malissa Shaw

    I purchased this product for my mother. The drops do burn when put into the eyes. So far she hasn’t noticed any discernible improvement in her vision, but it has only been 30-days, so we will keep trying to give it a fair shot.

    Malissa Shaw

  23. David Freyling

    Do not know how.well ocu phase is working as of yet have only used for one week at one drop in each eye twice a day so it’s to soon to tell

    David Freyling

  24. Eric Smead

    I only recently received this product, but so far I am impressed with the clarity I have gained. I’m not sure if it is just my desire to have it that way, but I believe it is doing what it says it is supposed to. Further use of the product, I think, is required. And perhaps a later review would be much more favorable than three stars which is all I feel I can give at this point. If the product continues to do as it has so far, I believe a five star rating is there. Thank you so much for this product.

    Eric Smead

  25. Denise Kinne

    i have not received my order yet but have used the drops once before. i found it was difficult to get the opening just right for the drops to come out properly. i hope I’ll have better luck next time.

    Denise Kinne

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Weight .25 lbs

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