Background
Good nutrition is a key element of preventing numerous age-related issues, including the health of our eyes. As we age our eyes become more susceptible to a host of challenges that can lead to irritation, discomfort and changes to vision. Colors may be dulled or distorted, and there may be an annoying halo of light around bright objects, causing a glare effect.
Applying lubricating eye drops several times a day can help to alleviate discomfort. Additionally, a number of nutrients have been shown to benefit eye health and good vision. One of these, carnosine, is a dipeptide consisting of two amino acids (alanine and histidine) connected by a chemical bond. Based on research performed mainly by Russian scientists, it is believed that carnosine’s antioxidant properties support healthy vision by inhibiting a chemical process called glycation.
Glycation leads to deleterious chemical complexes called AGEs (advanced glycation end products) that result from common but undesirable reactions between blood sugars, such as glucose, and proteins in many parts of our bodies, including the lenses of our eyes. The sugar-protein complexes become chemically cross-linked and degrade cellular functions. The aptly named AGEs are thought to be an important factor in the aging process.
Carnosine eye drops have been shown to aid in delaying vision senescence in humans by restoring the natural structure of proteins in the lens.
N-Acetylcarnosine
N-acetylcarnosine (NAC), like its parent compound, carnosine, occurs naturally throughout the human body. Both compounds are found primarily in the heart and skeletal muscles (the word carnosine is derived from the Latin word for flesh) and in the brain. Carnosine was discovered in 1900 in Russia, and it is in Russia that most of the recent research on the N-acetylcarnosine derivative has been carried out. Research with N-acetylcarnosine, as with carnosine, demonstrates that it is effective for improving transmissivity of light through the lens.
The structural difference between NAC and carnosine is that one hydrogen atom in carnosine replaces an acetyl group (CH3CO-), and this substitution occurs at a nitrogen atom. An important chemical difference between carnosine and N-acetylcarnosine is that carnosine is relatively insoluble in lipids (fats and fatty compounds), whereas N-acetylcarnosine is relatively soluble in lipids (as well as in water).
This means that N-acetylcarnosine may pass through the lipid membranes of the corneal and lens cells more easily than carnosine, and may thereby gain access more readily to the cells interior, which is primarily aqueous. There, the N-acetylcarnosine is gradually broken down to carnosine (and, perhaps, to histidine), which then exerts its beneficial effects.
Conclusion
Carnosine and N-acetylcarnosine eye drops appear to be a safe, effective means for supporting eye health, comfort and quality of vision in aging humans.
* These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
William Hilmes –
I have used the product for about 30 days to clear up my Cataracts that was a level 2 out of 4 where 4 is blind. It is still too early to tell if it is helping. I will go back to my eye Doctor for an evaluation in 6 months to check to progress. I will post an update in 5 months. That will be in March of 3019.
William Hilmes –
Richard Butt –
too expensive!!! for limited efficacy
Richard Butt –
Lynda Williams –
I don?t think I have used them long enough for my cataracts. They do sting a little bit in the evening when I use them.
Lynda Williams –
Arthur Dobson –
I haven’t seen any change yet.
Arthur Dobson –
BARBARA MACLEAN –
I’ve only been using for about 2 weeks and haven’t noticed any change as yet. The drops definitely sting in my eyes and I’m not sure how much remain in my eyes after blinking and tearing from the stinging.
BARBARA MACLEAN –
Kathy Fry –
Too early to say how effective the drops are yet
Kathy Fry –
OWEN YODER –
I HAVE BEEN TAKING THESE FOR TWO AND ONE-HALF MONTHS. I HAVE NOT SEEN ANY DIFFERENCE YET, BUT AM HOPEFUL TO SEE SOME IMPROVEMENT IN THE FUTURE.
OWEN YODER –
Verna Latham –
Only have one month under my belt, but I think I’m getting some relief from dry eye – and want to strengthen my eyes (had cataract surgery the end of March 2016). The product is easy to use and the price is right.
Verna Latham –