OcuPhase Eyedrops

(361 customer reviews)
Soothing, Lubricating Eye Drops with NAC
  • Contains 1% NAC (N-acetylcarnosine), a naturally occurring antioxidant and antiglycating agent.
  • Safe for use by people with: Cataracts, Glaucoma, Age-Related Macular Degeneration (ARMD/AMD), and Floaters.
  • Research with N-acetylcarnosine, as with it’s parent compound carnosine, demonstrates that it is effective not only in supporting healthy vision but also in increasing the transmissivity of the lens to light.
  • Helps to combat “dry eye” and other forms of eye irritation, such as blurry vision, night glare, and computer eye strain.
  • Each box of OcuPhase contains two resealable vials containing a total of about 200 drops.

9935 in stock


9935 in stock

361 reviews for OcuPhase Eyedrops

5 Star
236 review(s)
4 Star
88 review(s)
3 Star
25 review(s)
2 Star
8 review(s)
1 Star
4 review(s)

Reviewed by 276 customer(s)

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    thank you

    thank you

    July 18, 2021
    Verified Purchase


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    Perfect, except for the new packaging

    The OccuPhase product works great for me and I have used it for years – the product itself gets 5 stars. I have chronic dry eyes and other vision issues that come with aging and computer use that cause eye strain. I find that using this product before bed really works during the night to help restore my eyes.

    I was very disappointed with the last order I received that contained the new packaging. It took days of trying to get even one drop out of the bottle and it is very difficult to use and the hole sometimes closes up even after it has worked before.

    Please fix the packaging to make this product easier to use, like before. I will reorder and try again, but if the issue is the same, I may need to look for a different product.

    July 7, 2021
    Verified Purchase


  • Avatar

    Athena Weimer

    Works for me

    Been using them for a couple years now they help my dry eye. my night driving and I wrote reviews before but you have to write a review to get the 10% off your next order. being returned customers they should just automatically give the return customers 10% off without writing a review. and I am happy with the new bottles I really like the new bottles . thank you for the good product that helps me very much

    June 19, 2021
    Verified Purchase


    • Tango Advanced Nutrition

      June 21, 2021

      Hi Athena, we greatly appreciate your feedback, which is a valuable source of information for others, but you don’t need to write a review to get a 10% off coupon. Simply respond with Thank You in the response field and we’ll happily send you a discount code.

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    They are woring

    I bought these drops because I have potential cataracts and read that the active ingredient, NAC would help with them. Well it is working. My pupils are less constricted and my vision is better! Yay!

    June 18, 2021
    Verified Purchase


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    Daniel George Ferguson

    727 Return Message Tango

    Dear Manager,
    I have been successfully using your OccuPhase drops for over four years and believe that they are effective. My age is almost 86 years.
    I am saddened to have to return the items on my Order #15197 for a full refund because the items are not usable. I have only opened one box, but because the Lot #120120 is the same on all six boxes I assume they are all the same. The reason for return is:
    1. The plastic cap does not have a sharp plastic tip on the inside of the cap to puncture the container tip.
    a. Instead, it has a large half sphere approximately a tenth of an inch in diameter. Obviously, this will not puncture the container tip.
    b. This is contrary to your instruction sheet Step #1: Opening the Container, Puncture the Tip: etc.
    2. I tried puncturing the container tip with a common pin.
    a. It was successful, but when I installed the cap, it caused the tip to be blocked because the plastic flowed under the pressure of the half sphere in the cap.
    b. (I realize that the original design cap, which has a sharp plastic tip on the inside and each time it was installed, it maintained the size of the hole in the tip and kept the fluid in the container from being exposed to the outside air.)
    I expect that you are actively working on a fix for this problem. Please let me know when I can place an order for the final configuration. Thank you.
    Looking forward to your reply.

    Daniel Ferguson

    June 13, 2021
    Verified Purchase


    • Tango Advanced Nutrition

      June 18, 2021

      Hi Daniel, thanks for your feedback, and I understand your frustration. The last year has strained our access to our usual bottles due to an industry-wide, global need for materials and resources to manufacture life saving medical products (PPE, airway tubes, hypos, etc.). We expect to resolve the issue soon and will let you know when we are ready with a new, improved design. Regards, Jim English.

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    Raymond eckert

    Comfortable eyes

    Compared to other eye drops used, eyes feel more comfortable after applying these drops .

    June 8, 2021
    Verified Purchase


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    Jean Carroll


    Thank you!

    June 5, 2021
    Verified Purchase


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    I wanted to tell you how thrilled I am to be able to purchase OcuPhase eye drops and have them sent to Australia. I have been diagnosed with Serious Retinopathy in my left eye and have been told that the very best eye drops for this condition and that may help with my eye eventual improvement are your eye drops.

    And I always know my order will come through Australia Post and will arrive safely and quickly .

    June 3, 2021
    Verified Purchase


  • Avatar

    George Ulrich

    Thank You

    thank You . I stiil need to use them more often to give a good review !

    June 3, 2021
    Verified Purchase


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    May 27, 2021


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Suggested Use: For general preventive use, the recommended amount is 1–2 drops daily. Those with eye problems may want to use 2 drops twice daily or as needed.

OcuPhase also contains 1% N-acetylcarnosine, a naturally occurring antioxidant and antiglycating agent that helps protect the active ingredients from glycation. OcuPhase also contains ophthalmic lubricating agents to combat “dry eye” and other forms of eye irritation. Each box contains two vials containing five milliliters each.

Each package contains two resealable vials containing a total of about 200 drops, which allows for only a small amount of product to be exposed to oxygen at a time. Unopened vials can be stored in the refrigerator to extend shelf life.


  • If you experience eye pain, changes in vision, continued redness or irritation of the eye, or if the condition worsens or persists for more then 72 hours, discontinue use and consult a doctor.
  • To avoid contamination, do not touch tip of container to any surface.
  • Replace cap after using.
  • Do not use if seal is broken.
  • If solution changes color or becomes cloudy, do not use.

Not recommended for pregnant or nursing women.


Active Ingredients: Glycerin (lubricant) 1.0%, hydroxypropylmethylcellulose (lubricant) 0.15%

Inactive Ingredients: Sterile water (ophthalmic grade isotonic solution, pH 6.3 to 6.4), N-acetylcarnosine (NAC) 1.0%, buffered with boric acid, citric acid, and potassium bicarbonate, and, as a preservative, purified benzyl alcohol.


Good nutrition is a key element of preventing numerous age-related issues, including the health of our eyes. As we age our eyes become more susceptible to a host of challenges that can lead to irritation, discomfort and changes to vision. Colors may be dulled or distorted, and there may be an annoying halo of light around bright objects, causing a glare effect.

Applying lubricating eye drops several times a day can help to alleviate discomfort. Additionally, a number of nutrients have been shown to benefit eye health and good vision. One of these, carnosine, is a dipeptide consisting of two amino acids (alanine and histidine) connected by a chemical bond. Based on research performed mainly by Russian scientists, it is believed that carnosine’s antioxidant properties support healthy vision by inhibiting a chemical process called glycation.

Glycation leads to deleterious chemical complexes called AGEs (advanced glycation end products) that result from common but undesirable reactions between blood sugars, such as glucose, and proteins in many parts of our bodies, including the lenses of our eyes. The sugar-protein complexes become chemically cross-linked and degrade cellular functions. The aptly named AGEs are thought to be an important factor in the aging process.

Carnosine eye drops have been shown to aid in delaying vision senescence in humans by restoring the natural structure of proteins in the lens.


N-acetylcarnosine (NAC), like its parent compound, carnosine, occurs naturally throughout the human body. Both compounds are found primarily in the heart and skeletal muscles (the word carnosine is derived from the Latin word for flesh) and in the brain. Carnosine was discovered in 1900 in Russia, and it is in Russia that most of the recent research on the N-acetylcarnosine derivative has been carried out. Research with N-acetylcarnosine, as with carnosine, demonstrates that it is effective for improving transmissivity of light through the lens.

The structural difference between NAC and carnosine is that one hydrogen atom in carnosine replaces an acetyl group (CH3CO-), and this substitution occurs at a nitrogen atom. An important chemical difference between carnosine and N-acetylcarnosine is that carnosine is relatively insoluble in lipids (fats and fatty compounds), whereas N-acetylcarnosine is relatively soluble in lipids (as well as in water).

This means that N-acetylcarnosine may pass through the lipid membranes of the corneal and lens cells more easily than carnosine, and may thereby gain access more readily to the cells interior, which is primarily aqueous. There, the N-acetylcarnosine is gradually broken down to carnosine (and, perhaps, to histidine), which then exerts its beneficial effects.


Carnosine and N-acetylcarnosine eye drops appear to be a safe, effective means for supporting eye health, comfort and quality of vision in aging humans.

* These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.


What is the recommended daily use of OcuPhase?

For general preventive use, the recommended amount is 1–2 drops daily. Those with eye problems may want to use 2 drops twice daily or as needed.

Can children use OcuPhase?

OcuPhase eyedrops are not recommended for children under the age of 12 years.

What if I experience any discomfort when using OcuPhase eyedrops?

If the eye tissue becomes more inflamed, red, irritated or uncomfortable after using this product, immediately discontinue the use of product and consult an eye physician if necessary.

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