Coughing is an obvious sign of poor health and the leading reason for patient visits to doctors. Over one billion dollars are spent annually on over-the-counter (OTC) cough remedies for cough issues, yet the American College of Chest Physicians (ACCP) has recently reported that OTC cough expectorants and suppressants don’t address the underlying causes of the cough, and often don’t help at all. Antibiotics are also of limited value, since 95% of all coughs are viral in nature. Antibiotics may be helpful for reducing phlegm, but they can weaken the immune system. Traditional Chinese healing practices takes a different approach to cough, relying on classical formulas, some dating back to the 15th century, that remain popular today and continue to be used by millions of people throughout Asia. Significantly, a growing body of scientific research has shed light on properties of traditional herbal ingredients historically used to support lung health. Andrographis (Chuan Xin LIan, Andrographis Paniculata) Andrographis has been shown to be a safe traditional botanical for supporting upper respiratory tract health, per analysis of seven double-blind controlled trials. (1) Andrographis has been shown to inhibit RANTES secretion in inflamed bronchial cells. (2) RANTES is a chemoattractant for eosinophils, monocytes and lymphocytes that is stored in, and released by, platelets and activated T-cells. In related research:
 Andrographolide, an active ingredient in Andrographis, has been shown to be responsible for the herb’s inflammatory modulating actions, including the reduction of cytokine and peritoneal deposition of neutrophils, and modulation of lung inflammation in vivo. (3) Extracts of Andrographis exhibit potent inflammatory modulating and antioxidant actions in mouse models. (4)
Scutellaria (Huang Qin, Radix Scutellaria Baicalenses) Scutellaria root has a long history of use in China to support a healthy immune system. (5,6) In related research:
 Baicalein, a major flavonoid in Scutellaria, supports cardiovascular health. (7) Research shows that Scutellaria root modulates inflammatory activity to inhibit nitric oxide (NO), cytokine, chemokine and growth factor production in macrophages. (8) Scutellaria has been shown to inhibit histamine and leukotriene release. (9)
Gardenia Jasminoides (Zhi Zi, Gardenia Jasminoides) Genipen, an active ingredient in Gardenia, regulates inflammatory activity in mice study. (10) Geniposide from Gardenia enhances glutathione content in rat livers. Glutathione is an important immune system amino acid that helps determine modulation of immune response, including cytokine production. (11) Morus Alba (Sang Bai Pi, Radicis Cortex Morus Alba) Morus alba extracts have been shown to regulate mast cell degranulation and histamine release. (12) In a related study, a polysaccharide from Morus root has been shown to have immune-modulating activity. (13) Belamcanda (She Gan, Rhizoma Belamcandae Chinensis) An active ingredient from Belamcanda, irigenin, has inflammatory modulating properties in macrophage immune cells. (14) Asparagus (Tian Men Dong, Asparagus Cochinchinensis) Extracts from Asparagus root have been shown to modulate inflammatory actions. (15) Trichosanthes (Gua Lou Ren, Semen Trichosanthes) Trichosanthes seed extracts contain inflammatory regulating ingredients, including triterpenes. (16) Fritillaria (Chuan Bei Mu, Bulbus Fritillaria Chirrhosa) Fritillaria bulb is considered an anti-tussive herb, with imperialine identified as the major bioactive component. (17) Platycodon (Jie Geng, Radix Platycodon Grandiflorum) Platycodon root has been widely used in China for upper respiratory inflammatory issues. Active ingredients platycodon D and D3 increase mucin release in rat and hamster tracheal cells and provide useful expectorant effects. (18) In related research:
 Platycodon extracts exhibit inflammatory modulating effects on human-cultured airway epithelial cells. (19) Platycodon regulates inflammation via diverse pathways including modulation of IL-8 secretion by microglial cells. (20)
Stemona (Bai Bu Radix Stemona) Stemonines from Stemona root display anti-tussive activity in a guinea pig cough model. (21) In related research, stilbenoids, including resveratrol from Stemona root, inhibit leukotriene formation. (22) Licorice (Gan Cao, Radix Glycyrrhiza Uralensis) Glycyrrhizin from Glycyrrhiza root helps to modulate airway constriction, lung inflammation and infiltration of eosinophils in bronchial areas. (23) In related research:
 Glycyrrhiza root promotes CD4 and CD8 immune cell function. (24) A related study identifies the main anti-tussive active ingredients in glycyrrhiza root in various phases of the cough response. (25)
Safety
BronchoPhase is appropriate for all ages, including children above the age of 6. For infants less than 6 years of age Chinese herbs should be given only by an experienced practitioner.
References
1. Coon JT, Ernst E. Andrographis paniculata: a systematic review of safety and efficacy, Planta, 2004 Apr. Pubmed ID: 15095142. 2. Ko HC, Wei BL, Chiou WF. The effect of medicinal plants used in Chinese folk medicine on RANTES, Ethnopharmacol, 2006 Mar 17. Pubmed ID: 16621378. 3. Xia YF, Ye BQ, Li YD, Wang JG, He XY, Lin X, Yao X, Ma D, Slungaard A, Hebbel RP, Key NS, Geng JG. Andrographolide modulates inflammation by inhibition of NF-kappa B activation through covalent modification of reduced cysteine 62 of p50, Immunol. 2004 Sep 15. Pubmed ID: 15356172. 4. Sheeja K, Shihab PK, Kuttan G. Antioxidant and inflammatory modulating activities of the plant Andrographis paniculata Nees, Immunopharmacol Immunotoxicol. 2006. Pubmed ID: 16684672. 5. Yang ZC, Wang BC, Yang XS, Wang Q, Ran L. The synergistic activity with eight traditional Chinese medicines, Colloids Surf B Biointerfaces, 2005 Mar 25;41(2-3):79-81. Pubmed ID: 15737531. 6. Ma SC, Du J, But PP, Deng XL, Zhang YW, Ooi VE, XU HX, Lee SH, Lee SF. Chinese medicinal herbs, J Ethnopharmacol 2002 Feb, Pubmed ID: 11801383. 7. Huang Y, Tsang SY, Yao X, Chen ZY. Biological properties of baicalein in cardiovascular system, Curr Drug Targets Cardiovasc Haematol Disord, 2005 Apr;5(2):177-84. Pubmed ID: 15853750. 8. Kim EH, Shim B, Kang S, Jeong G, Lee JS, Chun M., Inflammatory Modulating Effects of Scutellaria baicalensis extract via Suppression of Immune Modulators and MAP kinase signaling molecules, J Ethnopharmacol. 2009 Aug 20. Pubmed ID: 19699788. 9. Lim BO., Effects of wogonin, wogonoside, and 3,5,7,2′,6′-pentahydroxyflavone on chemical mediator production in peritoneal exudate cells and immunoglobulin E of rat mesenteric lymph node lymphocytes, J Ethnopharmacol, 2003 Jan;84(1):23-9. Pubmed ID: 12499072. 10. Koo HJ, Lim KH, Jung HJ, Park EH. Evaluation of gardenia extract, geniposide and genipin, J Ethnopharmacol. 2006 Feb 20. Pubmed ID: 16169698. 11. Kang JJ, Wang HW, Liu TY, Chen YC, Ueng TH. Modulation of cytochrome P-450-dependent monooxygenases, glutathione and glutathione S-transferase in rat liver by geniposide from Gardenia jasminoides, Food Chem Toxicol., 1997 Oct-Nov. Pubmed ID: 9463529. 12. Chai OH, Lee MS, Han EH, Kim HT, Song CH., Morus Alba (Radicis Cortex Morus Alba) (Sang Bai Pi) Effects of Morus alba on compound 48/80 and anti-chicken gamma globulin IgE- mediated mast cell activation, Biol Pharm Bull, 2005 Oct, Pubmed ID: 16204934. 13. Kim HM, Han SB, Lee KH, Lee CW, Kim CY, Lee EJ, Huh H., Immunomodulating activity of a polysaccharide isolated from Mori Cortex Radicis, Arch Pharm Res,, 2000 Jan, Pubmed ID: 10896055, 14. Ahn KS, Noh EJ, Cha KH, Kim YS, Lim SS, Shin KH, Jung SH. Inhibitory effects of Irigenin from the rhizomes of Belamcanda chinensis on nitric oxide and prostaglandin E(2) production in murine macrophage RAW 264.7 cells, Life Sci., 2006 Apr 11;78(20):2336-42. Pubmed ID: 16307761. 15. Kim H, Lee E, Lim T, Jung J, Lyu Y., Modulating effect of Asparagus cochinchinensis on tumor necrosis factor-alpha secretion from astrocytes, Int J Immunopharmacol. 1998 Apr-May;20(4-5):153-62. Pubmed ID: 9730251. 16. Ozaki Y, Xing L, Satake M. Iinflammatory modulating effect of Trichosanthes kirilowii Maxim, and its effective parts, Biol Pharm Bull, 1996 Aug;19(8):1046-8. Pubmed ID: 8874813. 17. Chan SW, Li SL, Lin G, Li P., Pharmacokinetic study and determination of imperialine, the major bioactive component in antitussive Fritillaria cirrhosa, in rat by high-performance liquid chromatography coupled with evaporative light-scattering detector Anal Biochem. 2000 Oct 1;285(1):172-5. Pubmed ID: 10998280. 18. Shin CY, Lee WJ, Lee EB, Choi EY, Ko KH., Platycodin D and D3 increase airway mucin release in vivo and in vitro in rats and hamsters, Planta Med., Mar. Pubmed ID: 11914958. 19. Lee JH, Choi YH, Kang HS, Choi BT., An aqueous extract of Platycodi radix inhibits LPS-induced NF-kappaB nuclear translocation in human cultured airway epithelial cells, Int J Mol Med., 2004 Jun. Pubmed ID: 15138622. 20. Jang MH, Kim CJ, Kim EH, Kim MG, Leem KH, Kim J., Effects of Platycodon grandiflorum on lipopolysaccharide-stimulated production of prostaglandin E2, nitric oxide, and interleukin-8 in mouse microglial BV2 cells, J Med Food, 2006 Summer. Pubmed ID: 16822201. 21. Lin LG, Zhong QX, Cheng TY, Tang CP, Ke CQ, Lin G, Ye Y. Stemoninines from the roots of Stemona tuberosa, J Nat Prod., 2006 July. Pubmed ID: 16872143. 22. Adams, M, Pacher T, Greger H, Bauer R., Inhibition of leukotriene biosynthesis by stilbenoids from Stemona species, J Nat Prod., 2005 Jan. Pubmed ID: 15679323. 23. Ram A, Mabalirajan U, Das M, Bhattacharya I, Dinda AK, Gangal SV, Ghosh B. Glycyrrhizin, Int Immunopharmacol., 2006 Sept. Pubmed ID: 16846841. 24. Brush, Mendenhall E, Guggenheim A, Chan T, Connelly E, Soumyanath A, Buresh R, Barrett R, Zwickey H., The effect of Echinacea purpurea, Astragalus membranaceus and Glycyrrhiza glabra on CD69 expression and immune cell activation in humans, Phytother Res., 2006 Jun 28. Pubmed ID: 16807880. 25. Kamei J, Saitoh A, Asano T, Nakamura R, Ichiki H, Iiduka A, Kubo M., Pharmacokinetic and pharmacodynamic profiles of the antitussive principles of Glycyrrhizae radix (licorice), a main component of the Kampo preparation Bakumondo-to (Mai-men-dong-tang), Eur J Pharmacol, 2005 Jan 10. Pubmed ID: 15659306.
* These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Roberta Russell (verified owner) –
Good
Roberta Russell –
Dianne (verified owner) –
I have been using BronchoPhase for several years and it has helped me on multiple occasions. I highly recommend this supplement.
Dianne –
Debra (verified owner) –
I can feel the difference when i take this
Debra –
Roberta Russell (verified owner) –
Satisfied
Roberta Russell –
Les Von Bargen –
Items were shipped and received promptly. Price was lower than other sources.
Les Von Bargen –
Phyllis O’Meara –
I received my order very quickly and it was all good.
Phyllis O’Meara –
Malissa Daniel-Beeson (verified owner) –
I use one capsule of BronchoPhase every other day to break up the phlegm in my bronchial area. It works. Much less congestion.
Malissa Daniel-Beeson –
Carol –
This product keeps me congestion free all winterLast year I did not get my normal bronchitisI put that down to this great product
Carol –
Velma Dauer (verified owner) –
My husband has a cough, probably “medication-related”, which flares up occasionally. I make sure that we have a supply of BronchoPhase on hand at all times, because it really helps with his flare-ups.
Velma Dauer –
Benan Sanlier –
Like always come on the time and its works for me. ?
I recommend to everyone check their other products.
Benan Sanlier –
Theresa Rhodes (verified owner) –
Good product really helps husband
Theresa Rhodes –
Andrew Unruh –
This product is an all time winter favorite .. taken with ImmunoPhase one of each every hr until my condition improves, then take as recommended until discomfort is gone!
Andrew Unruh –
Lisa –
This is my second time using bronchophase for a persistent racking cough that just would not give up. The first time I had a cough after bronchitis even after several doctor visits and many drugs later it was two years and still coughing! My friend told me about bronchophase and gave me a bottle. I started taking it and the cough went away! I could not believe it. So for the past month I have had bronchitis again and went the usual route, but the cough persisted. Then I remembered the bronchophase and it has been just 24 hours and the cough is already getting better! Thank you for having this cure available, it has far exceeded my expectations!
Lisa –
Velma Dauer –
My husband has found that BrochoPhase helps to relieve his chest congestion. (You should know that he isn’t really keen on taking supplements) This, however, is a supplement that he wants to have on hand all the time and lets me know when I need to re-order!
Velma Dauer –
Teresa J Clapp –
This has really helped my husband and does what it says. Thanks!
Teresa J Clapp –
Andrea Huff –
love this product and wouldn’t start winter without it. I give as gift. Saves lung infections when sore throat and cough get worse
Andrea Huff –
Ange Nshamihigo –
You are the most in your service when you set an order to Tango Product you get what you want quickly .
Ange Nshamihigo –
STEWART T MCGRATH –
A very helpful supplement in the winter months.
STEWART T MCGRATH –
Liz Hildebrand –
BronchoPhase is my go to product when I feel that my respiratory health is compromised. It has always brought me relief for which I am very grateful.
Liz Hildebrand –
Gail Dutto (verified owner) –
This product has become a necessary supplement following a bout with pneumonia. It works!
Gail Dutto –
Penelope Raphaely –
Bronchcophase seem to shorten my chest infections considerably. The capsules are easy to take .
Penelope Raphaely –
Jeraldine Rogers –
I have been using bronchial phase four years and believe it has helped my lungs which were attacked by a bacterial infection.
I totally trust tango and their products and highly recommend them.
Jeraldine Rogers –
Carol Nottingham –
Have been using these 2 products for years & they really seem to help ward off colds & viruses.
Carol Nottingham –
Ramona Slate –
I have used this product for years. I love it. Makes your lungs feel great.
Ramona Slate –
Joy –
I keep this on hand for myself, family and friends. If I feel that my chest is getting congested I begin taking Broncho Phase and it knocks it right out. Simply put, it works for me!
Joy –
Barbara –
Great product.
Barbara –
Kate Walker –
This is the most remarkable product. It eases my chest discomfort so that I can breathe easier and have more energy. Thank you.
Kate Walker –
Velma Dauer –
My husband relies on BronchoPhase for support when he has chest congestion and discomfort, saying it really helps him. We always keep this product on hand!
Velma Dauer –
John Barnes –
helps keep my lungs clear
John Barnes –
Barbara –
BroncoPhase has been excellent in managing my husband’s pollen issues in the Spring and Fall for the past several years. We also take it at the first sign of a bug. It always seems to help; and as Barney Fife would say, it “nips it in the bud.”
Barbara –
Nancy R Hill –
I contracted an upper respiratory infection with a deep rattling cough and extreme tiredness. I took BronchoPhase along with ImmunoPhase and Herbal Boost and while I am still coughing some in the morning (1 week later), the cough never became the burning, aching cough that I normally develop that hangs on for weeks and weeks. I’ll keep BronchoPhase on hand for my next encounter!
Nancy R Hill –
Dianne Gardner (verified owner) –
I keep a bottle of BronchoPhase on hand at all times for use when I have respiratory discomfort. I take BronchoPhase to help keep seasonal bugs from developing into deeper bronchial issues.
Dianne Gardner –
G Lawson –
We used this during a recent issue with coughing and congestion. It seemed to help us get through the discomfort more quickly and gave significant relief. It is part of our “keep at all times” arsenal of natural remedies.
G Lawson –
Barbara Raphael –
Excellent product! We use it to curb my husband’s spring and fall pollen issues. And it works!
Barbara Raphael –
Marilynn Ives (verified owner) –
We have been taking the CardioPhase and Vital Cell now for a couple years and I would not be comfortable stopping it as it really makes a difference in our overall health.
The Bronco is a life saver. We have both recently had something and BroncoPhase is the one thing that made a true difference in our breathing and coughing. Will not be without it.
Marilynn Ives –
J Smith –
Really pleased with this company,fast delivery to the uk. So far so good lets hope they keep helping me great product.
J Smith –
Mary Ann Kooker –
With lifetime respiratory issues, Broncho Phase helps me by not having to use my “rescue inhaler” nearly so often.
Mary Ann Kooker –
Barbara Raphael –
I have actually been purchasing BroncoPhase for several years, and for a couple of reasons: 1. As a cancer and heart patient, I do not take over-the-counter medications or prescription drugs except in extreme circumstances. BroncoPhase is not a drug. 2. BroncoPhase helps stop or diminish a respiratory before it even has a chance to get into the chest. Don’t know why, but it works for head discomfort as well! I can’t remember the last time I felt ill! 3. My husband has always had spring and fall issues with pollen. I tried BroncoPhase on him almost four years ago. He starts taking it as soon as his symptoms begin and he hasn’t had any problem, spring or fall, since then! BroncoPhase is a great product from a company I have come to trust over the years.
Barbara Raphael –
Catherine Lawson –
We keep BroncoPhase on hand, especially in the winter, to help with respiratory discomfort. It works! We find it helps to clear the lungs. We use it on an as needed basis.
Catherine Lawson –
Lina –
My husband and I have used BronchoPhase for 4 weeks now. When the winter season starts, we both would have upper respiratory symptoms during this time of the year. So far we are still in good shape!
Lina –
Gertrud Takano –
For many years I had bronchial issues each winter. It first started as simple cough but then would go deeper and hurt my lungs. But then 6 or 5 years ago I started to take ImmonoPhasse and BronchoPhase before the winter started. Since then I never experienced the problem again and even when everybody around me is fighting off something I get through winters without any symptoms of cough. Also the family of my son take this supplements and are mostly fine. The only disadvantage is may be the large size of the caps especially for the children.
Gertrud Takano –
Gail Dutto (verified owner) –
Every product I purchase and receive from Tango Advanced Nutrition is always of the highest quality and consistently effective. My acupuncturist introduced me to these products years ago. I’m so grateful he did!
Gail Dutto –
Barbara Raphael –
Excellent Product
Barbara Raphael –
Gail Dutto (verified owner) –
Excellent lung support! Particularly in the Sierra Foothills where it can tend to be smoky (fire season) this time of year. Thanks for such a great product!!
Gail Dutto –
Lorraine –
Dear John, My husband was coughing day and night. We went to the doctors and they gave him a nasal spray. I don’t know what good that did. It sure didn’t stop the coughing. Then I read about BronchoPhase and ImmunoPhase and thought I’d try your products. I started my husband on BronchoPhase, and his chest cleared on the first day after taking the first two capsules! I continued to give him the full-recommended dosage for the next 6 days, and he never had another issue after those first two capsules. I am still amazed that it worked completely after the first 2 capsules. If his response hadn’t been so dramatic I’d still wonder if the formula was helping, but this product is powerful. I now order ImmunoPhase, based on my experience with BronchoPhase, and I keep both of these formulas on hand in case. Lorraine
Lorraine –
Nedra Fetterman, Ph.D. –
Please let your readers know that I had some kind of bug in mid-September. It seemed to resolve in a few days except for a persistent cough. After six weeks of coughing, I took a single dose of BroncoPhase and the tightness in my chest eased and the cough almost disappeared. I could not have been happier and I am so grateful for your BroncoPhase formula. Thank you so very, very much. Nedra Fetterman, Ph.D.
Nedra Fetterman, Ph.D. –
Susan F –
Dear Tango, This is an unsolicited testimonial for the products AllerPhase, BronchoPhase and ImmunoPhase. I am a recently retired first grade school teacher and a new grandmother of a three-year-old and 5-month-old. Both while teaching and now being around the grandchildren I am exposed to a large number of classroom bugs. Prior to taking BronchoPhase, whenever I would catch something it would always settle in my chest and I would end up with a cough for weeks at a time. It seemed like I was either catching something or getting over something all the time. Then BronchoPhase was introduced to me through Dr. David William’s monthly newsletter. I decided to try the product last winter and saw that ImmunoPhase was also available. I placed an order for both of these products. When they arrived, I had a couple of questions and called the company. They had the person who had developed these products call me back and he was able to completely answer all the questions I had. That winter, whenever I would start to feel something coming on, or when I was around the children who were coughing, I would start on the ImmunoPhase. The very minute I notice that my chest was feeling a little tight I started in on the BronchoPhase also. I was healthy the entire winter…the first time ever that I can remember. I also suffer from seasonal issues with pollens, so this past spring I used AllerPhase anytime I was going to be outside for any length of time. I was pleasantly surprised that I only had trouble once because I had forgotten to take my bottle of AllerPhase with me on a trip. I started taking the capsules on my return home and the problem immediately came under control. I never forget to have some AllerPhase capsules with me all the time. Usually it takes just one capsule to get results. I will not be without these products. It is the first time in a long time that I feel I have some control over seasonal health issues. Please feel free to use part or all of this testimonial. Sincerely, Susan Finney
Susan F –
Don G –
Dear Tango, I have a 64-year-old female patient who is plagued by yearly bouts of coughing, arriving with regularity in early winter and again in early spring. Her first symptoms are basic, with a sore, scratchy throat followed by “swollen glands” in her neck and under her jaw. From there, if not dealt with immediately, it drops into her chest and remains there for six to eight weeks. Her symptoms at that point will include “high-pitched wheezy noises” from her chest when lying down that “sound like small animals fighting” (patient’s description), plus frequent, persistent coughing spasms that can be so severe she loses bladder control. The patient must sleep sitting up in order to breathe at night. Her energy is very low throughout the illness. She first came to me during what she described as the “worst part” of her illness, and presented with a deep cough, sneezing, severe fatigue, and a slight temperature, 99.4 degrees. I prescribed BronchoPhase (3 caps every three hours) plus ImmunoPhase (2 caps every three hours). After a few days she had cleared up “dramatically, much quicker than it had in previous years.” She was, of course, thrilled with the results. We can now work on building her immune system to prevent future issues, but it’s great to know we have something in the arsenal that works so well. Thanks, Don Gates, L.Ac.
Don G –